Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice

Merkel cell carcinoma (MCC) is a rare and deadly neuroendocrine skin tumor frequently associated with clonal integration of a polyomavirus, MCPyV, and MCC tumor cells express putative polyomavirus oncoproteins small T antigen (sTAg) and truncated large T antigen (tLTAg). Here, we show robust transfo...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Invest Dermatol
Auteurs principaux: Verhaegen, Monique E., Mangelberger, Doris, Harms, Paul W., Vozheiko, Tracy D., Weick, Jack W., Wilbert, Dawn M., Saunders, Thomas L., Ermilov, Alexandre N., Bichakjian, Christopher K., Johnson, Timothy M., Imperiale, Michael J., Dlugosz, Andrzej A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397111/
https://ncbi.nlm.nih.gov/pubmed/25313532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.446
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