High-Resolution N(6)-Methyladenosine (m(6)A) Map Using Photo-Crosslinking-Assisted m(6)A Sequencing()

N(6)-methyladenosine (m(6)A) is an abundant internal modification in eukaryotic mRNA and plays regulatory roles in mRNA metabolism. However, methods to precisely locate the m(6)A modification remain limited. We present here a photo-crosslinking-assisted m(6)A sequencing strategy (PA-m(6)A-seq) to mo...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Chen, Kai, Lu, Zhike, Wang, Xiao, Fu, Ye, Luo, Guan-Zheng, Liu, Nian, Han, Dali, Dominissini, Dan, Dai, Qing, Pan, Tao, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396828/
https://ncbi.nlm.nih.gov/pubmed/25491922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201410647
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