Mapk/Erk activation in an animal model of social deficits shows a possible link to autism

BACKGROUND: There is converging preclinical and clinical evidence to suggest that the extracellular signal-regulated kinase (ERK) signaling pathway may be dysregulated in autism spectrum disorders. METHOD: We evaluated Mapk/Erk1/2, cellular proliferation and apoptosis in BTBR mice, as a preclinical...

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Detalhes bibliográficos
Publicado no:Mol Autism
Main Authors: Faridar, Alireza, Jones-Davis, Dorothy, Rider, Eric, Li, Jiang, Gobius, Ilan, Morcom, Laura, Richards, Linda J, Sen, Saunak, Sherr, Elliott H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396809/
https://ncbi.nlm.nih.gov/pubmed/25874073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-5-57
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