Quantitative Trait Loci for Interhemispheric Commissure Development and Social Behaviors in the BTBR T(+) tf/J Mouse Model of Autism

BACKGROUND: Autism and Agenesis of the Corpus Callosum (AgCC) are interrelated behavioral and anatomic phenotypes whose genetic etiologies are incompletely understood. We used the BTBR T(+) tf/J (BTBR) strain, exhibiting fully penetrant AgCC, a diminished hippocampal commissure, and abnormal behavio...

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Main Authors: Jones-Davis, Dorothy M., Yang, Mu, Rider, Eric, Osbun, Nathan C., da Gente, Gilberto J., Li, Jiang, Katz, Adam M., Weber, Michael D., Sen, Saunak, Crawley, Jacqueline, Sherr, Elliott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626795/
https://ncbi.nlm.nih.gov/pubmed/23613947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061829
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