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The potential of follicle-stimulating hormone peptide-modified triptolide-loaded nanoparticles to induce a mouse model of premature ovarian insufficiency

The use of triptolide (TP) is limited by its poor water solubility and severe toxicity. In this study, we developed an active drug delivery system (TP-loaded nanoparticles) that could help improve the water solubility of TP and decrease its toxicity. Then, we investigated whether TP-loaded nanoparti...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Chen, Xiu-Ying, Chen, Wu-Lian, Ma, Min, Gu, Chao, Xiao, Xi-Rong, Li, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396643/
https://ncbi.nlm.nih.gov/pubmed/25897221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S72593
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