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COMT polymorphism influences decrease of ovarian follicles and emerges as a predictive factor for premature ovarian insufficiency

BACKGROUND: Estrogens are important factors in the female reproductive functions and are processed by a number of enzymes along their metabolic pathway. The COMT gene constitutes a crucial element in estrogen metabolism and is assumed to be involved in the development of Premature Ovarian Insufficie...

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Detalhes bibliográficos
Main Authors: Cordts, Emerson Barchi, Santos, Monise Castro, Peluso, Carla, Kayaki, Erika Azuma, Bianco, Bianca, Barbosa, Caio Parente, Christofolini, Denise Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012167/
https://ncbi.nlm.nih.gov/pubmed/24808926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-7-47
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