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Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles

A hyperbranched cationic polysaccharide derivative-mediated small interfering (si)RNA interference strategy was proposed to inhibit nuclear transcription factor-kappa B (NF-κB) activation in human retinal pigment epithelial (hRPE) cells for the gene therapy of diabetic retinopathy. Two hyperbranched...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Liu, Zhenzhen, Gong, Haijun, Zeng, Rui, Liang, Xuan, Zhang, Li-Ming, Yang, Liqun, Lan, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396640/
https://ncbi.nlm.nih.gov/pubmed/25897219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S75188
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