The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques

There are no approved therapies for muscle wasting in children infected with human immunodeficiency virus (HIV), which portends poor disease outcomes. To determine whether a soluble ActRIIb receptor Fc fusion protein (ActRIIB.Fc), a ligand trap for TGF-β/activin family members including myostatin, c...

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Vydáno v:FASEB J
Hlavní autoři: O’Connell, Karyn E., Guo, Wen, Serra, Carlo, Beck, Matthew, Wachtman, Lynn, Hoggatt, Amber, Xia, Dongling, Pearson, Chris, Knight, Heather, O’Connell, Micheal, Miller, Andrew D., Westmoreland, Susan V., Bhasin, Shalender
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2015
Témata:
Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396606/
https://ncbi.nlm.nih.gov/pubmed/25466897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-257543
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