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Streptozotocin-induced type 1 diabetes in rodents as a model for studying mitochondrial mechanisms of diabetic β cell glucotoxicity

Chronic hyperglycemia and the corresponding glucotoxicity are the main pathogenic mechanisms of diabetes and its complications. Streptozotocin (STZ)-induced diabetic animal models are useful platforms for the understanding of β cell glucotoxicity in diabetes. As diabetes induced by a single STZ inje...

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Detalhes bibliográficos
Publicado no:Diabetes Metab Syndr Obes
Main Authors: Wu, Jinzi, Yan, Liang-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396517/
https://ncbi.nlm.nih.gov/pubmed/25897251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S82272
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