Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes

BACKGROUND AND PURPOSE: Aminoguanidine (AG), an inhibitor of advanced glycation endproducts, has been shown to prevent arterial stiffening and cardiac hypertrophy in streptozotocin (STZ) and nicotinamide (NA)-induced type 2 diabetes in rats. Our aims were to examine whether AG produced benefits on c...

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Detalhes bibliográficos
Main Authors: Wu, M-S, Liang, J-T, Lin, Y-D, Wu, E-T, Tseng, Y-Z, Chang, K-C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2439860/
https://ncbi.nlm.nih.gov/pubmed/18376420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.119
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