S-nitrosoglutathione reductase–dependent PPARγ denitrosylation participates in MSC-derived adipogenesis and osteogenesis

Bone marrow–derived mesenchymal stem cells (MSCs) are a common precursor of both adipocytes and osteoblasts. While it is appreciated that PPARγ regulates the balance between adipogenesis and osteogenesis, the roles of additional regulators of this process remain controversial. Here, we show that MSC...

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發表在:J Clin Invest
Main Authors: Cao, Yenong, Gomes, Samirah A., Rangel, Erika B., Paulino, Ellena C., Fonseca, Tatiana L., Li, Jinliang, Teixeira, Marilia B., Gouveia, Cecilia H., Bianco, Antonio C., Kapiloff, Michael S., Balkan, Wayne, Hare, Joshua M.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2015
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396480/
https://ncbi.nlm.nih.gov/pubmed/25798618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73780
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