S-nitrosoglutathione reductase–dependent PPARγ denitrosylation participates in MSC-derived adipogenesis and osteogenesis

Bone marrow–derived mesenchymal stem cells (MSCs) are a common precursor of both adipocytes and osteoblasts. While it is appreciated that PPARγ regulates the balance between adipogenesis and osteogenesis, the roles of additional regulators of this process remain controversial. Here, we show that MSC...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cao, Yenong, Gomes, Samirah A., Rangel, Erika B., Paulino, Ellena C., Fonseca, Tatiana L., Li, Jinliang, Teixeira, Marilia B., Gouveia, Cecilia H., Bianco, Antonio C., Kapiloff, Michael S., Balkan, Wayne, Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396480/
https://ncbi.nlm.nih.gov/pubmed/25798618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73780
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