Normalization of Naxos plakoglobin levels restores cardiac function in mice

Arrhythmogenic cardiomyopathy (AC) is associated with mutations in genes encoding intercalated disc proteins and ultimately results in sudden cardiac death. A subset of patients with AC have the autosomal recessive cardiocutaneous disorder Naxos disease, which is caused by a 2–base pair deletion in...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Zhang, Zhiwei, Stroud, Matthew J., Zhang, Jianlin, Fang, Xi, Ouyang, Kunfu, Kimura, Kensuke, Mu, Yongxin, Dalton, Nancy D., Gu, Yusu, Bradford, William H., Peterson, Kirk L., Cheng, Hongqiang, Zhou, Xinmin, Chen, Ju
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2015
Sujets:
Brief Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396479/
https://ncbi.nlm.nih.gov/pubmed/25705887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80335
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