Normalization of Naxos plakoglobin levels restores cardiac function in mice

Arrhythmogenic cardiomyopathy (AC) is associated with mutations in genes encoding intercalated disc proteins and ultimately results in sudden cardiac death. A subset of patients with AC have the autosomal recessive cardiocutaneous disorder Naxos disease, which is caused by a 2–base pair deletion in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Zhang, Zhiwei, Stroud, Matthew J., Zhang, Jianlin, Fang, Xi, Ouyang, Kunfu, Kimura, Kensuke, Mu, Yongxin, Dalton, Nancy D., Gu, Yusu, Bradford, William H., Peterson, Kirk L., Cheng, Hongqiang, Zhou, Xinmin, Chen, Ju
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2015
Pynciau:
Brief Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396479/
https://ncbi.nlm.nih.gov/pubmed/25705887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80335
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg