Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes

Accumulating evidence suggests that viruses play an important role in the development of diabetes. Although the diabetogenic encephalomyocarditis strain D virus induces diabetes in restricted lines of inbred mice, the susceptibility genes to virus-induced diabetes have not been identified. We report...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Izumi, Kenichi, Mine, Keiichiro, Inoue, Yoshitaka, Teshima, Miho, Ogawa, Shuichiro, Kai, Yuji, Kurafuji, Toshinobu, Hirakawa, Kanako, Miyakawa, Daiki, Ikeda, Haruka, Inada, Akari, Hara, Manami, Yamada, Hisakata, Akashi, Koichi, Niho, Yoshiyuki, Ina, Keisuke, Kobayashi, Takashi, Yoshikai, Yasunobu, Anzai, Keizo, Yamashita, Teruo, Minagawa, Hiroko, Fujimoto, Shuji, Kurisaki, Hironori, Shimoda, Kazuya, Katsuta, Hitoshi, Nagafuchi, Seiho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396380/
https://ncbi.nlm.nih.gov/pubmed/25849081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7748
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados