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PD-L1 blockade improves immune dysfunction of spleen dendritic cells and T-cells in zymosan-induced multiple organs dysfunction syndromes

This research is to investigate the role of tolerant spleen dendritic cells (DC) in multiple organs dysfunction syndromes (MODS) at late stage. Tolerant DC and MODS were induced by intraperotineal injection of zymosan. The immunity of DC was determined by examining interleukin (IL)-10, IL-12, IL-2,...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Liu, Qian, Lv, Yi, Zhao, Min, Jin, Yiduo, Lu, Jiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396242/
https://ncbi.nlm.nih.gov/pubmed/25973021
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