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Downregulated miR-29c correlates with increased BACE1 expression in sporadic Alzheimer’s disease

Background: Beta-site Amyloid precursor protein Cleaving Enzyme 1 (BACE1) is conceived as a potential target for therapies against Alzheimer disease (AD) which is characterized by the accumulation of plaques formed of short β-amyloid (APPβ) peptides. Recently, such microRNAs, as miR-29a, miR-29b-1 h...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Lei, Xiaofeng, Lei, Lijian, Zhang, Zhelin, Zhang, Zhiqing, Cheng, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396232/
https://ncbi.nlm.nih.gov/pubmed/25973041
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