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Dynamin2 downregulation delays EGFR endocytic trafficking and promotes EGFR signaling and invasion in hepatocellular carcinoma

Dysregulation of endocytosis was viewed as an emerging feature of cancer development and progression. A large GTPase dynamin2 plays a significant role in receptor tyrosine kinases (RTKs) endocytosis. The study was designed to investigate its roles in hepatocellular carcinoma (HCC) metastasis and its...

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Bibliografische gegevens
Gepubliceerd in:Am J Cancer Res
Hoofdauteurs: Gong, Chaojie, Zhang, Jubo, Zhang, Lan, Wang, Yingcong, Ma, Hui, Wu, Weizhong, Cui, Jiefeng, Wang, Yanhong, Ren, Zhenggang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396048/
https://ncbi.nlm.nih.gov/pubmed/25973308
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