Inhibition of autophagy enhances the anticancer activity of bortezomib in B-cell acute lymphoblastic leukemia cells

B-cell acute lymphoblastic leukemia (B-ALL) remains a challenging disease to treat in adults because of the high rates of relapse and refractory. Bortezomib, as a proteasome inhibitor, exerts obvious cytotoxicity against ALL cells and increases the sensitivity of ALL cells to conventional chemothera...

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Bibliografiske detaljer
Udgivet i:Am J Cancer Res
Main Authors: Wang, Zhihua, Zhu, Shicong, Zhang, Guangsen, Liu, Sufang
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396044/
https://ncbi.nlm.nih.gov/pubmed/25973303
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