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Semenogelin I promotes prostate cancer cell growth via functioning as an androgen receptor coactivator and protecting against zinc cytotoxicity

A seminal plasma protein, semenogelin I (SgI), contributes to sperm clotting, upon binding to Zn(2+), and can be proteolyzed by prostate-specific antigen (PSA), resulting in release of the trapped spermatozoa after ejaculation. In contrast, the role of SgI in the development and progression of any t...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Ishiguro, Hitoshi, Izumi, Koji, Kashiwagi, Eiji, Zheng, Yichun, Li, Yi, Kawahara, Takashi, Miyamoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396034/
https://ncbi.nlm.nih.gov/pubmed/25973311
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