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Wnt signaling through Snail1 and Zeb1 regulates bone metastasis in lung cancer

Wnt-β-catenin signaling participates in the epithelial-mesenchymal transition (EMT) in a variety of cancers; however, its role in lung cancer induced bone metastasis and the underlying mechanisms remain unclear. Here, we demonstrate that β-catenin, Snail1 and Zeb1 were significantly upregulated in b...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Yang, Xinghai, Li, Lei, Huang, Quan, Xu, Wei, Cai, Xiaopan, Zhang, Jishen, Yan, Wangjun, Song, Dianwen, Liu, Tielong, Zhou, Wang, Li, Zhenxi, Yang, Cheng, Dang, Yongyan, Xiao, Jianru
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396030/
https://ncbi.nlm.nih.gov/pubmed/25973312
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