Analysis of Dibenzo[def,p]chrysene-Deoxyadenosine Adducts in Wild-Type and Cytochrome P450 1b1 Knockout Mice using Stable-Isotope Dilution UHPLC-MS/MS

The polycyclic aromatic hydrocarbon (PAH), dibenzo[def,p]chrysene (DBC; also known as dibenzo[a,l]pyrene), is a potent carcinogen in animal models and a class 2A human carcinogen. Recent investigations into DBC-mediated toxicity identified DBC as a potent immunosuppressive agent similar to the well-...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Mutat Res Genet Toxicol Environ Mutagen
Autors principals: Harper, Tod A., Morré, Jeff, Lauer, Fredine T., McQuistan, Tammie J., Hummel, Jessica M., Burchiel, Scott W., Williams, David E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395865/
https://ncbi.nlm.nih.gov/pubmed/25868132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrgentox.2015.03.007
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars