The B Cell Adaptor Molecule Bam32 Is Critically Important for Optimal Antibody Response and Resistance to Trypanosoma congolense Infection in Mice

BACKGROUND: Bam32, a 32 kDa adaptor molecule, plays important role in B cell receptor signalling, T cell receptor signalling and antibody affinity maturation in germinal centres. Since antibodies against trypanosome variant surface glycoproteins (VSG) are critically important for control of parasite...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Onyilagha, Chukwunonso, Jia, Ping, Jayachandran, Nipun, Hou, Sen, Okwor, Ifeoma, Kuriakose, Shiby, Marshall, Aaron, Uzonna, Jude E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395458/
https://ncbi.nlm.nih.gov/pubmed/25875604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003716
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