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TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection

It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes. However, the intracellular signaling pathways leading to the production of these cytokines still remain unknown. In this paper, we have investi...

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Publicado en:Front Immunol
Main Authors: Kuriakose, Shiby, Onyilagha, Chukwunonso, Singh, Rani, Olayinka-Adefemi, Folayemi, Jia, Ping, Uzonna, Jude E.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883972/
https://ncbi.nlm.nih.gov/pubmed/31824484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02673
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