3β-Hydroxysterol Δ24-Reductase on the Surface of Hepatitis C Virus-Related Hepatocellular Carcinoma Cells Can Be a Target for Molecular Targeting Therapy

In our previous study, we demonstrated that 3β-hydroxysterol Δ24-reductase (DHCR24) was overexpressed in hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC), and that its expression was induced by HCV. Using a monoclonal antibody against DHCR24 (2-152a MAb), we found that DHCR24 was speci...

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Vydáno v:PLoS One
Hlavní autoři: Saito, Makoto, Takano, Takashi, Nishimura, Tomohiro, Kohara, Michinori, Tsukiyama-Kohara, Kyoko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395381/
https://ncbi.nlm.nih.gov/pubmed/25875901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124197
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