Simvastatin Modulates Mesenchymal Stromal Cell Proliferation and Gene Expression

Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway, responsible for the biosysnthesis of cholesterol. However, statins also have pleiotropic effects that interfere with several signaling pathways. Mesenchymal stromal cells (MSC) are a heterogeneous mixture of cells t...

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Vydáno v:PLoS One
Hlavní autoři: Zanette, Dalila Lucíola, Lorenzi, Julio Cesar Cetrulo, Panepucci, Rodrigo Alexandre, Palma, Patricia Vianna Bonini, dos Santos, Daiane Fernanda, Prata, Karen Lima, Silva, Wilson Araújo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395223/
https://ncbi.nlm.nih.gov/pubmed/25874574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120137
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