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Simvastatin Modulates Mesenchymal Stromal Cell Proliferation and Gene Expression
Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway, responsible for the biosysnthesis of cholesterol. However, statins also have pleiotropic effects that interfere with several signaling pathways. Mesenchymal stromal cells (MSC) are a heterogeneous mixture of cells t...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4395223/ https://ncbi.nlm.nih.gov/pubmed/25874574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120137 |
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