API5 confers tumoral immune escape through FGF2-dependent cell survival pathway

Identifying immune escape mechanisms used by tumors may define strategies to sensitize them to immunotherapies to which they are otherwise resistant. In this study, we show that the anti-apoptotic gene API5 acts as an immune escape gene in tumors by rendering them resistant to apoptosis triggered by...

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Pubblicato in:Cancer Res
Autori principali: Noh, Kyung Hee, Kim, Seok-Ho, Kim, Jin Hee, Song, Kwon-Ho, Lee, Young-Ho, Kang, Tae Heung, Han, Hee Dong, Sood, Anil K., Ng, Joanne, Kim, Kwanghee, Sonn, Chung Hee, Kumar, Vinay, Yee, Cassian, Lee, Kyung-Mi, Kim, Tae Woo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394897/
https://ncbi.nlm.nih.gov/pubmed/24769442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3225
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