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Evolution of Hepatitis C Virus Quasispecies during Repeated Treatment with the NS3/4A Protease Inhibitor Telaprevir

In treating hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infections, the rapid reselection of resistance-associated variants (RAVs) is well known in patients with repeated exposure to the same class of antiviral agents. For chronic hepatitis C patients who have experienced virologi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Susser, Simone, Flinders, Mathieu, Reesink, Henk W., Zeuzem, Stefan, Lawyer, Glenn, Ghys, Anne, Van Eygen, Veerle, Witek, James, De Meyer, Sandra, Sarrazin, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394796/
https://ncbi.nlm.nih.gov/pubmed/25712364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04911-14
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