Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment

The BRAF inhibitor vemurafenib is currently used for treating patients with BRAF V600E mutant melanoma. However, the responses to vemurafenib are generally partial and of relatively short duration. Recent evidence suggests that activation of the epidermal growth factor receptor (EGFR)/erbB signaling...

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Bibliografiske detaljer
Udgivet i:Melanoma Res
Main Authors: Ng, Yuen-Keng, Lee, Jia-Ying, Supko, Kathryn M., Khan, Ayesha, Torres, Salina M., Berwick, Marianne, Ho, Jonhan, Kirkwood, John M., Siegfried, Jill M., Stabile, Laura P.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394744/
https://ncbi.nlm.nih.gov/pubmed/24709886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000060
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