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International Union of Basic and Clinical Pharmacology. XCV. Recent Advances in the Understanding of the Pharmacology and Biological Roles of Relaxin Family Peptide Receptors 1–4, the Receptors for Relaxin Family Peptides

Relaxin, insulin-like peptide 3 (INSL3), relaxin-3, and INSL5 are the cognate ligands for the relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates pleiotropic signaling pathways including the signalosome protein complex that facilitates high-sensitivity signaling; coupling to G...

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Bibliografske podrobnosti
izdano v:Pharmacol Rev
Main Authors: Halls, Michelle L., Bathgate, Ross A. D., Sutton, Steve W., Dschietzig, Thomas B., Summers, Roger J.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394689/
https://ncbi.nlm.nih.gov/pubmed/25761609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.114.009472
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