Methemoglobin Is an Endogenous Toll-Like Receptor 4 Ligand—Relevance to Subarachnoid Hemorrhage

Neuroinflammation is a well-recognized consequence of subarachnoid hemorrhage (SAH), and may be responsible for important complications of SAH. Signaling by Toll-like receptor 4 (TLR4)-mediated nuclear factor κB (NFκB) in microglia plays a critical role in neuronal damage after SAH. Three molecules...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kwon, Min Seong, Woo, Seung Kyoon, Kurland, David B., Yoon, Sung Hwan, Palmer, Andre F., Banerjee, Uddyalok, Iqbal, Sana, Ivanova, Svetlana, Gerzanich, Volodymyr, Simard, J. Marc
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394463/
https://ncbi.nlm.nih.gov/pubmed/25751721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16035028
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