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Inhibition of the Sur1-Trpm4 Channel Reduces Neuroinflammation and Cognitive Impairment in Subarachnoid Hemorrhage

BACKGROUND AND PURPOSE: Subarachnoid hemorrhage (SAH) can leave patients with memory impairments that may not recover fully. Molecular mechanisms are poorly understood, and no treatment is available. The sulfonylurea receptor 1–transient receptor potential melastatin 4 (Sur1-Trpm4) channel plays an...

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Detalhes bibliográficos
Main Authors: Tosun, Cigdem, Kurland, David B., Mehta, Rupal, Castellani, Rudy J., deJong, Joyce L., Kwon, Min Seong, Woo, Seung Kyoon, Gerzanich, Volodymyr, Simard, J. Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894855/
https://ncbi.nlm.nih.gov/pubmed/24114458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.002904
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