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Thrombospondin-1 Regulates Blood Flow via CD47 Receptor-Mediated Activation of NADPH Oxidase 1

OBJECTIVE: Although the matricellular protein thrombospondin-1 (TSP1) is highly expressed in the vessel wall in response to injury, its pathophysiological role in the development of vascular disease is poorly understood. This study was designed to test the hypothesis that TSP1 stimulates reactive ox...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Csányi, Gábor, Yao, Mingyi, Rodriguez, Andres I., Al Ghouleh, Imad, Sharifi-Sanjani, Maryam, Frazziano, Giovanna, Xiaojun, Huang, Kelley, Eric E., Isenberg, Jeffrey S., Pagano, Patrick J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394361/
https://ncbi.nlm.nih.gov/pubmed/23087362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300031
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