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Peptidic Inhibitors for in Vitro Pentamer Formation of Human Papillomavirus Capsid Protein L1
[Image: see text] A new 14 peptide, originating essentially from the helix 5 of HPV 16L1, illustrates an IC(50) of 19.38 nM for the inhibition of HPV 16 L1 pentamer formation, which is highly efficient for targeting a specific protein segment. In addition, mechanism studies reveal that the length, s...
Sparad:
I publikationen: | ACS Med Chem Lett |
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Huvudupphovsmän: | , , , , |
Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
American Chemical
Society
2015
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Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394338/ https://ncbi.nlm.nih.gov/pubmed/25893037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500392y |
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