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Peptidic Inhibitors for in Vitro Pentamer Formation of Human Papillomavirus Capsid Protein L1

[Image: see text] A new 14 peptide, originating essentially from the helix 5 of HPV 16L1, illustrates an IC(50) of 19.38 nM for the inhibition of HPV 16 L1 pentamer formation, which is highly efficient for targeting a specific protein segment. In addition, mechanism studies reveal that the length, s...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Fu, Ding-Yi, Jin, Shi, Zheng, Dong-Dong, Zha, Xiao, Wu, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394338/
https://ncbi.nlm.nih.gov/pubmed/25893037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500392y
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