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A Scalable Method for Molecular Network Reconstruction Identifies Properties of Targets and Mutations in Acute Myeloid Leukemia

A key aim of systems biology is the reconstruction of molecular networks. We do not yet, however, have networks that integrate information from all datasets available for a particular clinical condition. This is in part due to the limited scalability, in terms of required computational time and powe...

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Bibliografske podrobnosti
izdano v:J Comput Biol
Main Authors: Ong, Edison, Szedlak, Anthony, Kang, Yunyi, Smith, Peyton, Smith, Nicholas, McBride, Madison, Finlay, Darren, Vuori, Kristiina, Mason, James, Ball, Edward D., Piermarocchi, Carlo, Paternostro, Giovanni
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394180/
https://ncbi.nlm.nih.gov/pubmed/25844667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0297
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