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Identification of Drug Combinations Containing Imatinib for Treatment of BCR-ABL+ Leukemias

The BCR-ABL translocation is found in chronic myeloid leukemia (CML) and in Ph+ acute lymphoblastic leukemia (ALL) patients. Although imatinib and its analogues have been used as front-line therapy to target this mutation and control the disease for over a decade, resistance to the therapy is still...

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Главные авторы: Kang, Yunyi, Hodges, Andrew, Ong, Edison, Roberts, William, Piermarocchi, Carlo, Paternostro, Giovanni
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100887/
https://ncbi.nlm.nih.gov/pubmed/25029499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102221
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