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p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies

Ca(2+) transfer from the endoplasmic reticulum (ER) to the mitochondria critically controls cell survival and cell death decisions. Different oncogenes and deregulation of tumor suppressors exploit this mechanism to favor the survival of altered, malignant cells. Two recent studies of the Pinton tea...

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Publicado en:Oncoscience
Autores principales: Bittremieux, Mart, Bultynck, Geert
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394128/
https://ncbi.nlm.nih.gov/pubmed/25897426
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