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Multifunctional polymeric micelles co-loaded with anti-survivin siRNA and paclitaxel overcome drug resistance in an animal model of ovarian cancer

Ovarian cancer is a dreadful disease estimated to be the second most common gynecological malignancy worldwide. Its current therapy, based on cytoreductive surgery followed by the combination of platinum and taxanes, is frequently complicated by the onset of multidrug resistance (MDR). The discovery...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Salzano, Giuseppina, Navarro, Gemma, Trivedi, Malav S., De Rosa, Giuseppe, Torchilin, Vladimir P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394040/
https://ncbi.nlm.nih.gov/pubmed/25657335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0556
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