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Multifunctional polymeric micelles co-loaded with anti-survivin siRNA and paclitaxel overcome drug resistance in an animal model of ovarian cancer

Ovarian cancer is a dreadful disease estimated to be the second most common gynecological malignancy worldwide. Its current therapy, based on cytoreductive surgery followed by the combination of platinum and taxanes, is frequently complicated by the onset of multidrug resistance (MDR). The discovery...

詳細記述

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書誌詳細
出版年:Mol Cancer Ther
主要な著者: Salzano, Giuseppina, Navarro, Gemma, Trivedi, Malav S., De Rosa, Giuseppe, Torchilin, Vladimir P.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394040/
https://ncbi.nlm.nih.gov/pubmed/25657335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0556
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