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Valproic acid induces neuronal cell death through a novel calpain-dependent necroptosis pathway
A growing body of evidence indicates that valproic acid (VPA), a histone deacetylase (HDAC) inhibitor used to treat epilepsy and mood disorders, has HDAC-related and -unrelated neurotoxic activity, the mechanism of which is still poorly understood. We report that VPA induces neuronal cell death thro...
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| Publié dans: | J Neurochem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393803/ https://ncbi.nlm.nih.gov/pubmed/25581256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13029 |
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