The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

Despite recent discoveries of genetic variants associated with autoimmunity and infection, genetic control of the human immune system during homeostasis is poorly understood. We undertook a comprehensive immunophenotyping approach, analysing 78,000 immune traits in 669 female twins. From the top 151...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Roederer, Mario, Quaye, Lydia, Mangino, Massimo, Beddall, Margaret H., Mahnke, Yolanda, Chattopadhyay, Pratip, Tosi, Isabella, Napolitano, Luca, Barberio, Manuela Terranova, Menni, Cristina, Villanova, Federica, Di Meglio, Paola, Spector, Tim D., Nestle, Frank O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393780/
https://ncbi.nlm.nih.gov/pubmed/25772697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.046
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