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A Replicative Plasmid Vector Allows Efficient Complementation of Pathogenic Leptospira Strains

Leptospirosis, an emerging zoonotic disease, remains poorly understood because of a lack of genetic manipulation tools available for pathogenic leptospires. Current genetic manipulation techniques include insertion of DNA by random transposon mutagenesis and homologous recombination via suicide vect...

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Detalles Bibliográficos
Publicado en:Appl Environ Microbiol
Main Authors: Pappas, Christopher J., Benaroudj, Nadia, Picardeau, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393447/
https://ncbi.nlm.nih.gov/pubmed/25724960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00173-15
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