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Nucleic acid recognition orchestrates the anti-viral response to retroviruses
Intrinsic restriction factors and viral nucleic-acid sensors are important for the anti-viral response. Here, we show how upstream sensing of retroviral reverse transcripts integrates with the downstream effector APOBEC3, an IFN-induced cytidine deaminase that introduces lethal mutations during retr...
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| Publicado no: | Cell Host Microbe |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393365/ https://ncbi.nlm.nih.gov/pubmed/25816774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.02.021 |
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