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DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection

Host recognition of viral nucleic acids generated during infection leads to the activation of innate immune responses essential for early control of virus. Retrovirus reverse transcription creates numerous potential ligands for cytosolic host sensors that recognize foreign nucleic acids, including s...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Stavrou, Spyridon, Aguilera, Alexya N., Blouch, Kristin, Ross, Susan R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989071/
https://ncbi.nlm.nih.gov/pubmed/29871919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00923-18
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