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miR-217 mediates the protective effects of the dopamine D2 receptor on fibrosis in human renal proximal tubule cells

Lack or downregulation of the dopamine D2 receptor (D(2)R) increases the vulnerability to renal inflammation independently of blood pressure in mice. Common single nucleotide polymorphisms (SNPs) rs 6276, 6277 and 1800497 in the human D(2)R gene are associated with decreased receptor expression/func...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Han, Fei, Konkalmatt, Prasad, Chen, Jianghua, Gildea, John, Felder, Robin A., Jose, Pedro A., Armando, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393363/
https://ncbi.nlm.nih.gov/pubmed/25801876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05096
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