CHBPR: SINGLE NUCLEOTIDE POLYMORPHISMS OF THE DOPAMINE D2 RECEPTOR INCREASE INFLAMMATION AND FIBROSIS IN HUMAN RENAL PROXIMAL TUBULE CELLS

The dopamine D2 receptor (D(2)R) negatively regulates inflammation in mouse renal proximal tubule cells (RPTCs) and lack or downregulation of the receptor in mice increases the vulnerability to renal inflammation independent of blood pressure. Some common single nucleotide polymorphisms (SNPs; rs 62...

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Detalhes bibliográficos
Main Authors: Jiang, Xiaoliang, Konkalmatt, Prasad, Yang, Yu, Gildea, John, Jones, John E., Cuevas, Santiago, Felder, Robin A., Jose, Pedro A., Armando, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929206/
https://ncbi.nlm.nih.gov/pubmed/24379187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02569
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