Polycyclic Aromatic Hydrocarbons Reciprocally Regulate IL-22 and IL-17 Cytokines in Peripheral Blood Mononuclear Cells from Both Healthy and Asthmatic Subjects

Pollution, including polycyclic aromatic hydrocarbons (PAH), may contribute to increased prevalence of asthma. PAH can bind to the Aryl hydrocarbon Receptor (AhR), a transcription factor involved in Th17/Th22 type polarization. These cells produce IL17A and IL-22, which allow neutrophil recruitment,...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Plé, Coline, Fan, Ying, Ait Yahia, Saliha, Vorng, Han, Everaere, Laetitia, Chenivesse, Cécile, Balsamelli, Joanne, Azzaoui, Imane, de Nadai, Patricia, Wallaert, Benoit, Lazennec, Gwendal, Tsicopoulos, Anne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393221/
https://ncbi.nlm.nih.gov/pubmed/25860963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122372
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