Polycyclic Aromatic Hydrocarbons Reciprocally Regulate IL-22 and IL-17 Cytokines in Peripheral Blood Mononuclear Cells from Both Healthy and Asthmatic Subjects

Pollution, including polycyclic aromatic hydrocarbons (PAH), may contribute to increased prevalence of asthma. PAH can bind to the Aryl hydrocarbon Receptor (AhR), a transcription factor involved in Th17/Th22 type polarization. These cells produce IL17A and IL-22, which allow neutrophil recruitment,...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Plé, Coline, Fan, Ying, Ait Yahia, Saliha, Vorng, Han, Everaere, Laetitia, Chenivesse, Cécile, Balsamelli, Joanne, Azzaoui, Imane, de Nadai, Patricia, Wallaert, Benoit, Lazennec, Gwendal, Tsicopoulos, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393221/
https://ncbi.nlm.nih.gov/pubmed/25860963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122372
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