Polycyclic Aromatic Hydrocarbons Reciprocally Regulate IL-22 and IL-17 Cytokines in Peripheral Blood Mononuclear Cells from Both Healthy and Asthmatic Subjects

Pollution, including polycyclic aromatic hydrocarbons (PAH), may contribute to increased prevalence of asthma. PAH can bind to the Aryl hydrocarbon Receptor (AhR), a transcription factor involved in Th17/Th22 type polarization. These cells produce IL17A and IL-22, which allow neutrophil recruitment,...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Plé, Coline, Fan, Ying, Ait Yahia, Saliha, Vorng, Han, Everaere, Laetitia, Chenivesse, Cécile, Balsamelli, Joanne, Azzaoui, Imane, de Nadai, Patricia, Wallaert, Benoit, Lazennec, Gwendal, Tsicopoulos, Anne
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393221/
https://ncbi.nlm.nih.gov/pubmed/25860963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122372
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