Rab5a is a common component of the apical and basolateral endocytic machinery in polarized epithelial cells.

In nonpolarized cells, the small GTPase Rab5a is localized to the plasma membrane, clathrin-coated vesicles, and early endosomes. Rab5a is required for early endosome fusion in vitro and regulates transport between the plasma membrane and early endosomes, in vivo. In polarized epithelial cells endoc...

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Bibliografiske detaljer
Main Authors: Bucci, C, Wandinger-Ness, A, Lütcke, A, Chiariello, M, Bruni, C B, Zerial, M
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43931/
https://ncbi.nlm.nih.gov/pubmed/8197185
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